Rene's first project involved synthesizing 17O enriched versions of polyoxoniobates and studying the reactivity of various oxygen sites by 17O NMR. She followed isotopic oxygen exchange for the 19 non-equivalent oxygen sites in a tetrasiliconiobate ion to prepare for her future thesis work involving various NMR and computational methods to study uranyl complexes. Currently she is investigating the reactivity of uranyl monomers and polyoxo-uranyl compounds. This work includes studying 'yl' oxygen exchange and ligand exchange with variable pressure, as well as studying the stability and reaction dynamics of large uranyl clusters in an aqueous environment.