Representative Publications

Enantioselective Si-H Insertion Reactions of Diarylcarbenes for the Synthesis of Silicon-Stereogenic Silanes Jake R. Jagannathan, James C. Fettinger, Jared T. Shaw*, and Annaliese K. Franz* J. Am. Chem. Soc.  2020, 147, 11674-11679.

NMR Quantification of the Effects of Ligands and Counterions on Lewid Acid Catalysis Julia J. Jennings, Benjamin W. Wigman, Brittany M. Armstrong, and Annaliese K. Franz* J. Org. Chem  2019, 84, 15845-15853.

Catalytic Asymmetric Synthesis of Cyclopentene-spirooxindoles Bearing Vinylsilanes Capable of Further Transformations Angel A. Cobo, Brittany M. Armstrong, James C. Fettinger, and Annaliese K. Franz* Org. Lett.  2019, 21, 8196-8200.

Kinetic and Binding Studies Reveal Cooperativity and Off‐cycle Competition for H‐bonding Catalysis with Silsesquioxane Silanols Jake R. Jagnnathan, Kayla Diemoz, Karina Targos, James Fettinger, Annaliese K. Franz* Chem. Eur. J.  2019, 25.

Metal-Free Synthesis of 1,3-Disiloxanediols and Aryl Siloxanols Austin T. Kelly and Annaliese K. Franz* ACS Omega  2019, 4, 6295-6300.

Producing Oleaginous Microorganisms Using Wastewater: Methods and Guidelines for Lab- and Industrial-Scale Production Kayla M. Rude, Tyler J. Barzee, and Annaliese K. Franz* Microbial Lipid Production: Methods in Molecular Biology  2019, 1995, 327-355.

Conversion of Microbial Lipids to Biodiesel and Basic Lab Tests for Analysis of Fuel-Quality Parameters Annaliese K. Franz*, Cody Yothers Microbial Lipid Production: Methods in Molecular Biology  2019, 1995, 285-310.

Sodium-Catalyzed Friedel-Crafts Reactions and Mechanistic Insight Kelsey M. Mesa, Hailey A. Hibbard, and Annaliese K. Franz* Org. Lett.  2019, 21, 3877-3881.

EPR Evidence for the Origin of Nonlinear Effects in an Enantioselective Cu(II)-Catalyzed Spiroannulation Brittany M. Armstrong, Richard I. Sayler, Benjamin H. Shupe, Troy A. Stich, R. David Britt, and Annaliese K. Franz* ACS Catal.  2019, 9, 1224-1230.

NMR Quantification of Hydrogen-Bond-Activating Effects for Organocatalysts including Boronic Acids Kayla M. Diemoz and Annaliese K. Franz* J. Org. Chem.  2019, 84, 1126-1138.

Reaction Progress Kinetics Analysis of 1,3-Disiloxanediols as Hydrogen-Bonding Catalysts Kayla M. Diemoz, Jason E. Hein, Sean O. Wilson, James C. Fettinger, Annaliese K. Franz* J. Org. Chem.  2017, 82, 6738-6747.

Synthesis of Structurally Varied 1,3-Disiloxanediols and Their Activity as Anion-Binding Catalysts Kayla M. Diemoz, Sean O. Wilson, Annaliese K. Franz* Chem. Eur. J. 2016, 22, 18349.

Combined nitrogen limitation and hydrogen peroxide treatment enhances neutral lipid accumulation in the marine diatom Phaeodactylum tricornutum Andrew R. Burch, Annaliese K. Franz* Bioresour. Technol. 2016, 219, 559.

Lanthanum(III)-Catalyzed Three-Component Reaction of Coumarin-3-carboxylates for the Synthesis of Indolylmalonamides and Analysis of Their Photophysical Properties J. J. Jennings, C. P. Bhatt, A. K. Franz* J. Org. Chem.  2016, 81, 6211.

Chlorella vulgaris production enhancement with supplementation of synthetic medium in dairy manure wastewater Shi, J.; Pandey, P. K.*; Franz, A. K.; Deng, H.; Jeannotte, R. AMB Expr. 2016, 6, 15-23.

Titanium(IV)-Catalyzed Stereoselective Synthesis of Spirooxindole-1-pyrrolines J. J. Badillo, C. J. A. Ribeiro, M. M. Olmstead, A. K. Franz* Org. Lett 2014, 16, 6270.

Distinct Roles for Mitogen-Activated Protein Kinase Signaling and Calmodulin-Binding Transcriptional Activator3 in Regulating the Peak Time and Amplitude of the Plant General Stress Response M. Bjornson, G Benn, X. Song, L. Comai, A. K. Franz, A. M. Dandekar, G. Drakakaki, K. Dehesh* Plant Physiology 2014, 166, 988.

Catalytic Enantioselective Carboannulation with Allylsilanes N. R. Ball-Jones, J. J. Badillo, N. T. Tran, and A. K. Franz* Angew. Chem. Int. Ed. 2014, 53, 9462. Highlighted in Synfacts, 2014, 1062.

Counterion effects in the catalytic stereoselective synthesis of 2,3'-pyrrolidinyl spirooxindoles J. P. MacDonald, B. H. Shupe, J. D. Schreiber, and A. K. Franz* Chem. Commun. 2014, 50, 5242.

Supramolecular hydrogen-bonding assembly of silanediols with bifunctional heterocycles N. T. Tran, S. O. Wilson, and A. K. Franz* Chem. Commun. 2014, 50, 3738.

A comparison of lipid storage in Phaeodactylum tricornutum and Tetraselmis Suecica, using laser scanning confocal microscopy D. M. Wong, and A. K. Franz* J. Microbiol. Methods 2013, 95, 122.

Synthesis of Spirocarbamate Oxindoles via Intramolecular Trapping of a B-silyl Carbocation by an N-Boc Group B. H. Shupe, E. E. Allen, J. P. MacDonald, S. O. Wilson, and A. K. Franz* Org. Lett. 2013, 15, 3218.

Phenotypic Screening with Oleaginous Microalgae Reveals Modulators of Lipid Productivity A. K. Franz*, M. A. Danielwicz, and D. M. Wong, L. A. Anderson, and J. R. Boothe ACS Chem. Biol. 2013, 8, 1053.

Asymmetric Catalysis for the Synthesis of Spirocyclic Compounds A. K. Franz*, N. V. Hanhan, and N. R. Ball-Jones ACS Catal. 2013, 3, 540.

Organosilicon Molecules with Medicinal Applications S. O. Wilson, and A. K. Franz* J. Med. Chem. 2013, 56, 388.

An improved high-throughput Nile red fluorescence assay for estimating intracellular lipids in a variety of yeast species I. R. Sitepu, L. Ignatia, A. K. Franz, D. M. Wong, S. A. Faulina, M. Tsui, A. Kanti, K. Boundy-Mills J. Microbiol. Methods, 2012, 91, 321.

NMR and X-ray Studies of Hydrogen Bonding for Amide-Containing Silanediols S. O. Wilson, N. T. Tran, and A. K. Franz* Organometallics 2012, 31, 6715.

Real-Time Monitoring of Transesterification by 1H NMR Spectroscopy: Catalyst Comparison and Improved Calculation for Biodiesel Conversion L. A. Anderson, and A. K. Franz* Energy Fuels 2012, 26, 6404.

Enantiocontrol with a Hydrogen-bond Directing Pyrrolidinylsilanol Catalyst T. Min, J. C. Fettinger, and A. K. Franz* ACS Catal. 2012, 2, 1661.

Scandium(III)-Catalyzed Enantioselective Allylation of Isatins Using Allylsilanes N. V. Hanhan, Y. C. Tang, N. T. Tran, and A. K. Franz* Org. Lett. 2012, 14, 2218.

Strategies for the enantioselective synthesis of spirooxindoles N. R. Ball-Jones, J. J. Badillo and A. K. Franz* Org. and Biomol. Chem. 2012, 10, 5165.

Catalytic Stereoselective Synthesis of Diverse Oxindoles and Spirooxindoles from Isatins J. P. MacDonald, J. J. Badillo, G. E. Arevalo, A. Silva-Garcia and A. K. Franz* ACS Comb. Sci. 2012, 14, 285.

Catalytic Asymmetric [3+2] Annulation of Allylsilanes with Isatins: Synthesis of Spirooxindoles N. V. Hanhan, N. R. Ball-Jones, N. T. Tran and A. K. Franz* Angew. Chem. Int. Ed. 2012, 51, 989.

Cooperative Hydrogen-Bonding Effects in Silanediol Catalysis N. T. Tran, S. O. Wilson, and A. K. Franz* Org. Lett. 2012, 14, 186.

Enantioselective and Regioselective Indium(III)-Catalyzed Addition of Pyrroles to Isatins E. G. Gutierrez, C. J. Wong, A. H. Sahin, and A. K. Franz* Org. Lett. 2011, 13, 5754.

Enantioselective Pictet-Spengler Reactions of Isatins for the Synthesis of Spiroindolones J. J. Badillo, A. Silva-Garcia, B. H. Shupe, J. C. Fettinger, and A. K. Franz* Tetrahedron Lett.. 2011, 52, 5550.

Triacylglycerol Profiling of Marine Microalgae by Mass Spectrometry M. A. Danielewicz, L. A. Anderson, and A. K. Franz* J. Lipid. Research 2011, 52, 2101. Using MALDI-TOF and NMR spectroscopy to profile algae triacylglycerols relevant for biofuels and high-value lipid products.

Gas Phase Acidity Studies of Dual Hydrogen-Bonding Organic Silanols and Organocatalysts M. Liu, N. T. Tran, A. K. Franz,* and J. K. Lee* J. Org. Chem. 2011, 76, 7186-7194. Acidity studies comparing silanols, silanediols and other hydrogen-bonding organocatalysts

Silyl Fluoride Electrophiles for the Enantioselective Synthesis of Silylated Pyrrolidine Catalysts K. I. Jentzsch, T. Min, J. I. Etcheson, J. C. Fettinger, and A. K. Franz* J. Org. Chem. 2011, 76, 7065-7075. Silyl pyrrolidine catalysts for the Michael reaction and ESI-MS identification of a hydrogen-bonded pyrrolidine-nitrostyrene adduct

Silanediol Hydrogen-bonding Activation of Carbonyl Compounds N. T. Tran, T. Min, and A. K. Franz* Chem. Eur. J. 2011, 17, 9897-9900. Geo-inspired Catalysis: the first example of silanediols as organocatalysts and activation of carbonyls for the Diels-Alder reaction

Titanium-catalyzed Stereoselective Synthesis of Spirooxindole Oxazolines J. J. Badillo, G. E. Arevalo, J. C. Fettinger, and A. K. Franz* Org. Lett. 2011, 13, 418-421. New synthetic methodology and regiochemical reversal for spirocyclic oxazolines

Enantioselective Synthesis of Substituted Oxindoles and Spirooxindoles with Applications in Drug Discovery J. J. Badillo, N. V. Hanhan, and A. K. Franz* Curr. Opin. Drug Disc. Dev. 2010, 13, 758-766.

Catalytic Asymmetric Synthesis of Substituted 3-Hydroxy-2-Oxindoles N. V. Hanhan, A. H. Sahin, T. W. Chang, J. C. Fettinger, and A. K. Franz* Angew. Chem. Int. Ed. 2010, 49, 744-747. Highlighted in Synfacts 2010, 4, 449. A comparison of scandium(III) and indium(III) chiral complexes for enantioselective addition of various aromatic and non-aromatic nucleophiles to isatins.

The Synthesis of Biologically Active Organosilicon Small Molecules A. K. Franz* Curr. Opin. Drug Disc. Dev. 2007, 10, 654-671.

Synthesis and Cellular Profiling of Diverse Organosilicon Small Molecules A. K. Franz, P. D. Dreyfuss, and S. L. Schreiber J. Am. Chem. Soc. 2007, 129, 1020-1021

Diastereoselective Silacyclopropanations of Functionalized Chiral Alkenes T. G. Driver, A. K. Franz, and K. A. Woerpel J. Am. Chem. Soc. 2002, 124, 6524-6525.

ZnBr2-Catalyzed Insertions of Carbonyl Compounds into Silacyclopropanes: Regiochemical Reversal Dependent on Metal Salt A. K. Franz, and K. A. Woerpel Angew. Chem. Int. Ed. 2000, 39, 4295-4299.

Development of Reactions of Silacyclopropanes as New Nethods for Stereoselective Organic Synthesis A. K. Franz, and K. A. Woerpel Acc. Chem. Res. 2000, 33, 813-820.

Stereospecific and Regioselective Reactions and Silacyclopropanes with Carbonyl Compounds Catalyzed by Copper Salts: Evidence for a Transmetalation Mechanism A. K. Franz, and K. A. Woerpel J. Am. Chem. Soc. 1999, 121, 949-957.