Molinski Group - Recent Publications

The following is a list of recent publications from the Molinski group.

62.    MacMillan, J.B.; Molinski, T.F. "Herbacic Acid, A Simple Prototype of 5,5,5-Trichloroleucine Metabolites from the Sponge Dysidea herbacea" J. Nat. Prod. 2000, 63(1), 155-157.

63.    Nicholas, G.M.; Molinski, T.F.; "Enantiodivergent Biosynthesis of the Dimeric Sphingolipid Oceanapiside from the Marine Sponge Oceanapia phillipensis. Determination of Remote Stereochemistry" J. Am. Chem. Soc. 2000, 122(17), 4011-4019.

64.    Shafer, C.M.; Molinski, T.F. "A Practical Synthesis of Oxazole" Heterocycles 2000, 53(5), 1167-1170.

65.    Nicholas, G.M.; Molinski, T.F. "Structures of Cribochalines A and B, Branched-Chain Methoxylaminoalkyl Pyridines from the Micronesian Sponge, Cribochalina sp. Absolute Configuration and Enantiomeric Purity of Related O-Methyl Oximes", Tetrahedron 2000, 56(19), 2921-2927.

66.    MacMillan, J.B.; Trousdale, E.K.; Molinski, T.F. "Structure of (–)-Neodysidenin from Dysidea herbacea.  Implications for the Biosynthesis of 5,5,5-Trichloroleucine Peptides", Org. Lett. 2000, 2(17), 2721-2723.

67.    Molinski, T.F.; Makarieva, T.N.; Stonik, V.A. (–)-Rhizochalin is a Dimeric Enantiomorphic (2R)-Sphingolipid.  Analysis of pseudo-C2v Symmetric bis-2-Amino-3-Alkanols by CD", Angew. Chem., Intl. Ed. 2000, 39(22), 4076-4079.

68.    Haak, L.L; Song, L-S.; Molinski, T.F.; Pessah, I.N.; Cheng, H.; Russell, J.T. "Oligodendrocyte progenitor sparks and puffs; Crosstalk between ryanodine receptors and IP3 receptors" J. Neuroscience 2001, 21(11), 3860-3870.

69.    Franz, A.H.; Molinski, T.F.; Lebrilla, C.B. “MALDI-FTMS Characterization of Oligosaccharides Labeled with 9-Aminofluorene” J. Am. Soc. Mass Spec. 2001, 12(12), 1254-1261.

70.    Masuno, M.N.; Molinski, T.F. "Regioselective Cationic Reduction of 2-Aryl-1-N-(Ethoxycarbonyl)enamines to 2-Arylethylamine Carbamates", Tetrahedron Lett. 2001, 42(47), 8263-8266

71.    Moon, S.S.; MacMillan, J.B.; Olmstead, M.M.; Anh Ta, T.; Pessah, I.N.; Molinski, T.F., (+)-7S-Hydroxyxestospongin A from the Marine Sponge Xestospongia sp. and Absolute Configuration of (+)–Xestospongin D" J. Nat. Prod. 2002, 65(3), 249-254.

72.    MacMillan, J.B.; Molinski, T.F. "Lobacyclamide B from Lyngbya confervoides. Configuration and Asymmetric Synthesis of b-Hydroxy-a-Amino Acids by (–)-Sparteine-Mediated Aldol Addition" Org. Lett. 2002, 4(11), 1883-1886.

73.    Stanley, S.D.; Molinski, T.F. "Improved Synthesis of 13C,2H3- and 2H3-Salmeterol by Cs2CO3-Mediated Monoalkylation of a Primary Amine" J. Lab. Cpd. Radiopharm. 2002, 45, 755-762.

74.    Molinski, T.F.; Brzezinski, L.J.; Leahy, J.W. "Absolute Configuration of Phorboxazole A C32-43 Analogs by CD Exciton-Coupling of Allylic 2-Naphthoate Esters" Tetrahedron: Asymmetry 2002, 13(10), 1013-1016

75.    Nicholas, G.N.; Ronghua Li; MacMillan, J.B.; Molinski, T.F. "Antifungal Activity of Bifunctional Sphingolipids. Intramolecular Synergism within Long-Chain a,w-bis-Aminoalcohols" Bioorg. Med. Chem. Lett. 2002, 12, 2159-2162.

76.    MacMillan, J.B.; Molinski, T.F. "Caylobolide A, a Unique 36-Membered Macrolactone from a Bahamian Lyngbya majuscula" Org. Lett. 2002, 4(9), 1535-1538.

77.    MacMillan, J.B.; Ernst-Russell, M.A.; de Ropp, J.S.; Molinski, T.F. "Lobocyclamides A-C, Lipopeptides from a Cryptic Cyanobacterial Mat Containing Lyngbya confervoides" J. Org. Chem. 2002, 67(23), 8210-8215. 

78.    Bailey, K.L.; Molinski, T.F. "Synthesis of a Bastadin Analog Through an SNAr Coupling Strategy" Tetrahedron Lett. 2002, 43(52), 9657-9661.

79.    Masuno, M.N.; Molinski, T.F. "Cationic Reduction of Bastadin-4 to Bastadin-5.  Preparation of 5-2H-Bastadin-5 by Site-Specific Isotopic Labeling" J. Nat. Prod. 2003, 66(1), 112-114.

80.    Zhou, G-X.; Molinski, T.F. “Long-Chain Acetylenic Ketones from the Micronesian Sponge Haliclona sp.  Importance of the 1-yn-3-ol Group for Antitumor Activity” Mar. Drugs 2003, 1(1), 46-53.

81.        Richter, R.K.; Mickus, D.E.; Rychnovsky, S.D.; Molinski, T.F. “Differential Modulation of the Antifungal Activity of Amphotericin B by Natural and ent-Cholesterol” Bioorg. Med. Chem. Lett. 2004, 14(1), 115-118.

82.        Masuno, M.N.; Molinski, T.F. “Phorbasterones A-D. Cytotoxic Nor-Ring A Steroids from the Sponge Phorbas amaranthus” J. Nat. Prod. 2004, xx, xxxx, in press.

83.        Molinski, T.F. “Antifungal Compounds from Marine Organisms.” Curr. Topic. Med. Chem. 2004, xx, xxxx, submitted.

84.        Andersen , R.J.; Ireland, C.M.; Molinski, T.F.; Bewley, C..B.“D. John Faulkner: ASP Research Achievement Award” J. Nat. Prod. 2004, xx, xxxx, submitted.