CHE 235: Organometallic Chemistry in Organic Synthesis (Spring 2009)

Using current examples from the literature, the aim of this practical course is to discuss organometallic reagents and catalysts for organic synthesis. Throughout the course there will be a strong emphasis on structural and mechanistic details, and also a comparison to synthetic methods using organocatalysis and biocatalysis (when relevant). The design of this course is suitable for both 1st and 2nd year graduate students who are interested in the areas of organic synthesis, organometallic chemistry, and reaction mechanisms; advanced undergraduate students may also perform well in the course.

CHE 8A and 8B: Brief Organic Chemistry I and II

CHE 231B: Advanced Organic Synthesis (Spring 2010)

Current strategies and methods in synthetic organic chemistry; continuation of course 231A with an emphasis on stereochemical considerations and asymmetric synthesis; organometallics for selective transformations; carbocyclic and heterocyclic ring formation.

CHE 221E: Special Topics in Organic Chemistry, Catalysis in Modern Organic Synthesis

(Special topics class taught in Fall 2007)

Using current examples from the literature, the aim of this practical course is to discuss catalytic methodologies for organic synthesis, including the topics of organometallic catalysis, organocatalysis, and biocatalysis. Links will be made between organic chemistry and biochemical processes, with an introduction to the use of enzymes in organic synthesis. Throughout the course, there will be a strong emphasis on mechanism and the principles of catalysis. There is no specific textbook for the course since primary literature articles will serve as the foundation for our lectures and discussions. The design of this course is suitable for both 1st and 2nd year graduate students who are interested in the areas of organic synthesis, organometallic chemistry, and chemical biology; advanced undergraduate students may also perform well in the course. Instead of a final exam, there will be a final project/presentation so that each student can delve into the area of catalysis that interests him or her most.